After being forced off with an injury in the win over Derry, goalkeeper Shaun Patton was named in Donegal’s initial team but he misses out with Gavin Mulreanny stepping up.
Tyrone, meanwhile, had originally picked Joe Oguz at wing forward in place of Liam Gray.
However, three late changes see Michael O’Neill in for Oguz, with Aodhan Donaghy replaced by Conn Kilpatrick and Cathal McShane taking Ruairí Canavan’s place.
DONEGAL: G Mulreanny; M Curran, B McCole, C Moore; R McHugh, C McGonagle, P Mogan; J McGee, M Langan; S O’Donnell, C Thompson, D Ó Baoill; P McBrearty, O Gallen, N O’Donnell. Subs: Caolan McColgan, K McGettigan, S McMenamin, O Doherty, D Mac Giolla Bhride, J Mac Ceallbhuí, H McFadden, J Brennan, A Doherty, JR Molloy, C Mac Aonghása.
TYRONE: N Morgan; C Devlin, P Hampsey, M McKernan; S O’Donnell, M Donnelly, N Devlin; B Kennedy, C Kilpatrick; C Daly, K McGeary, M O’Neill; D McCurry, C McShane, R Canavan. Subs: L Quinn, A Clarke, B Cullen, C Cush, C Donnelly, A Donaghy, N McCarron, L McCarthy, R Canavan, D Jones, T Quinn.